Program in Cell and Tissue Engineering
ABOUT THE PROGRAM
The program seeks to develop engineering technologies using biomaterials, nanotechnology, microfabrication, and biophysical methods to study stem cells and how they form tissues and organs. Because the formation of functional tissues is relevant in a number of clinical regenerative medicine settings, this program interacts with many of the other programs within the IRM to provide enabling technologies.
BREAKTHROUGHS IN RESEARCH
- Researchers at Penn pioneered studies that discovered that physical forces can guide stem cell fates.
- Researchers are investigating how biomaterial properties can be used to enhance stem cell function.
- Scientists are developing engineered heart microtissue as a platform for screening drugs for cardiac safety.
ON THE HORIZON
- Investigators are developing novel biomaterials to enhance stem cell expansion, differentiation, and delivery for therapeutic applications.
- Scientists are developing bioreactors to guide stem cells to form functional tissues including heart, cartilage, bone, and liver.
- Nanotechnologies are being developed that can guide stem cell behaviors.